Certified Reference Materials (CRMs) for Paracetamol (Acetaminophen) and Related Compounds
Paracetamol (Acetaminophen) belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers). Since its approval in 1951, Paracetamol has become the most common drug ingredient in the USA, and is widely used throughout the world.
While it is generally considered to be safe medication when used as directed, it can be dangerous if taken at high, non-recommended doses. Ovedose of Paracetamol can cause serious (possibly fatal) liver disease and is the most common cause of acute liver failure in adults.
The FDA has recently taken action to improve the safety of consumers when using Paracetamol (Acetaminophen). The FDA issued a list of approximately 600 medications that contain the drug in a consumer update warning about the effects of doubling up on dosages of acetaminophen. In addition, the FDA is recommending that health care professionals discontinue prescribing and dispensing prescription combination drug products that contain more than 325 milligrams (mg) of acetaminophen per tablet.
As awareness about pharmaceutical waste and the impact on the environment grows, acetaminophen has been identified as one of the detectable pharmaceuticals in drinking water. Trace amounts (ppb or ppt) of Acetaminophen have been detected in drinking water supplies of several large metropolitan areas within the US.
Sigma-Aldrich offers Fluka brand Certified Reference Materials (CRMs) for Acetaminophen (Paracetamol) and several related compounds. These CRMs are Secondary Pharmaceutical Reference Standards and are traceable to and qualified against the corresponding Pharmacopoeial standards. A comprehensive Certificate of Analysis offers details of the methodology and results of the qualification.
The full catalogue of Sigma Aldrich, Fluka and Supelco products can be accessed from Greyhound Chromatography's home page www.greyhoundchrom.com
For over 40 years Greyhound Chromatography has been supplying high quality Chromatography consumables to laboratories around the world. Greyhound’s extensive range covers all areas of Environmental, Petrochemical, Food, Forensics, Chemical and Pharmaceutical analysis. Backed by a highly experienced technical services team, Greyhound is the preferred source amongst today’s analysts.
CONTACT US
Tel: +44 (0) 151 649 4000
Email: marketing@greyhoundchrom.com
FOLLOW US
YOU MAY ALSO BE INTERESTED IN OUR NEWSLETTER
About The Author
Susan Massie, Sales & Marketing Director, Greyhound Chromatography and Allied Chemicals Email: sue@greyhoundchrom.com
Susan Massie is the Sales & Marketing Director for Greyhound Chromatography and Allied Chemicals, affectionately known as 'Greyhound' in our scientific community. Greyhound was founded by Susan's husband Paul Massie almost 40 years ago, Susan hasn't been in the business for all of that time but has been involved with Greyhound for over 17 years. Greyhound continues to grow, expanding into new markets and taking on the challenges of our ever changing environment. It's heartwarming to witness the world waking up to the fact that we are damaging our planet on a daily basis. Every action we take has a direct effect on our planet and the world we leave behind for future generations. Susan is passionate about climate change and is happy to work in an industry that can have a direct effect on reducing the impact of our actions on the environment. All of the team at Greyhound take our responsibilities very seriously, the products that we supply are used by the world's leading scientists and chemists as they endeavour to monitor and repair the environment. All is not lost, if we all take responsibility for our actions, from reducing our waste and reusing or recycling our material collateral we can make a difference. The internet is full of useful advice and guidance, Susan is proud to contribute to that wealth of knowledge whenever she can.
Greyhound prides itself on personal service which provides prompt, efficient, cost-effective, safe delivery of all products. Greyhound provides technical advice and distribution of Certified Reference Standards and Materials, Laboratory Consumables, Solvents and Reagents across all scientific disciplines. Greyhound Chromatography offers over 1 Million products from its UK warehouse. The team at Greyhound are proud to support the work of the world's leading scientists and chemists as they challenge the abuse of our planet and try to make a difference to the world we leave behind for our ancestors.
You can view Susan's Linked In Profile here https://www.linkedin.com/in/susan-massie-79ab4121/