Hamilton PRP-X300 columns offer an easy,
rapid way to separate closely related alcohols
and organic acids.
The sulfonated poly(styrenedivinylbenzene)
support separates samples via
a mixed mode mechanism. Separation on the
PRP-X300 is accomplished by three modes:
hydrogen bonding, reversed-phase, and ion
exclusion. PRP-X300 column selectivity can be
altered by changing the pH of the buffer or adding
an organic modifier (e.g., methanol, acetonitrile).
The support’s stability to organic solvents makes
it possible to analyze samples that are too highly
retained on conventional ion exclusion supports.
The high performance packing ensures narrow
peaks under isocratic conditions. The use
of isocratic conditions allows samples to be
analyzed one after another without waiting for
column re-equilibration. Most samples require
only minimal preparation before injection,
increasing sample throughput in the lab.
PRP-X300
Pore Size: 100Å
Material: PS-DVB/ Sulfonic acid
Applications: Organic acids and alcohols
